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Namely, BPC 157 mitigated leaky gut syndrome by acting via increasing tight junction protein ZO-1 expression and transepithelial resistance [107]

Advanced MASH-related liver fibrosis is typically the result of a chronic, sustained inflammatory response involving multiple factors, characterized by abnormal deposition of type I collagen in the extracellular matrix (ECM), with the activation of HSCs being a key driver of liver fibrosis (Chan et al