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Nahra R, Wang T, Gadde KM, Oscarsson J, Stumvoll M, Jermutus L, et al

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DPP-4i could restore the inactivation of AKT and ERK signaling and inhibit NF-B activation to reduce the production of pro-inflammatory factors, including TNF-, IL-1, monocyte chemoattractant protein-1 (MCP-1), ICAM-1 and TGF- (169, 170)