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METHODS: Pancreatic islets isolated from normal Sprague-Dawley rats were incubated in high (20 mM) and low (5 mM) glucose concentration for 48 hours

LiYLiCYanJLiaoYQinCWangLet al

Not all the screen phenotypes could be confirmed in agar-overlay plaque assays, possibly due to variations in cell growth between liquid and solid media, or due to the requirement for successive complete infection cycles and sufficient burst sizes for the formation of visible plaques that would render plaque assays less sensitive than single-infection cycle dynamics in our screen