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P53 mutations are highly prevalent in breast tumors [197] potentially granting a survival advantage to breast cancer cells as they navigate mechanically challenging microenvironments

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Lilly Zepbound / Mounjaro (tirzepatide) ~21% mean weight loss at ~72 weeks (top dose) Clear superiority vs Wegovy Growing long-term durability data Takeaway: Zepbound remains the benchmark every obesity drug must beat or meaningfully out-differentiate

This excess fat acts like a clog in the system, interfering with the livers ability to filter toxins and regulate blood sugar