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Mechanistically, circadian control of CI probably reflects the intersection of substrate routing and time-of-day coordination of CI biogenesis, stability and activity

The mean SD of reduced GSH level for the age groups 1530 years, 3145 years, and over 46 years were 7.13 2.23, 5.14 1.42, and 2.55 0.464 ng/mL, respectively, for Group A, whereas the mean SD of reduced GSH level for the age groups 1530 years, 3145 years, and over 46 years were 17.99 3.29, 15.88 3.31, and 13.6 2.31 ng/mL, respectively, for Group B

doi:10.2337/db13-1093 Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, Yorek MA, Beebe D, Oates PJ, Hammes HP, Giardino I, Brownlee M (2000) Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage