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2025;25(1):533.[DOI] 167

Journal of Psychoactive Drugs

Despite limited value of individual tau protein biomarkers in the early diagnosis of PD, the t-tau/t--Syn ratio, when combined with t--Syn levels in CSF, can greatly increase the accuracy of early PD diagnosis by allowing for better differentiation from AD or DLB (Frland et al., 2020)