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Data availability Data will be available on request Abbreviations CitAgNPs: Citrusfusion silver nanoparticles FTIR: Fourier Transform Infrared Spectroscopy FESEM: Field Emission Scanning Electron Microscopy EDAX: Energy Dispersive X-ray Analysis MIC: Minimum Inhibitory Concentration MFC: Minimum Fungicidal Concentration References de Oliveira Santos GC, Vasconcelos CC, Lopes AJ, de Sousa Cartgenes MD, Filho AK, Do Nascimento FR, Ramos RM, Pires ER, de Andrade MS, Rocha FM, de Andrade Monteiro C

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Sermorelin's FDA Journey: Approved, Discontinued, and Compounded Sermorelin acetate (Geref) was FDA-approved in 1997 for pediatric GHD 1 and in 1990 for diagnostic use.26 The manufacturer discontinued Geref in 2008 due to "manufacturing difficulties," not safety or efficacy concerns.12 In 2013, the FDA confirmed it wasn't withdrawn for safety/effectiveness, allowing for potential generic approvals.12 Currently, Sermorelin is primarily available as a compounded medication 3, which is permitted but not individually FDA-approved like mass-produced drugs.22 5.2

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