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The chemical concentration and treatment duration for each assay were set in accordance with the protocols used in our previously published studies 17,18,19 or pilot studies

While the lack of significant differences in heart rate overall may suggest that L-carnitine does not directly affect the cardiovascular response, the early-stage reduction in heart rate supports the idea that supplementation could improve the body's ability to handle increasing workloads more efficiently (Table 3)

Consequently, pathological accumulation of aberrant mitochondria exacerbates mitochondrial dysfunction

Adipocyte-derived LCN2 promotes lipolysis and muscle atrophy through transcriptional activation of MuRF-1 and Atrogin-1 expression during pancreatic cancer cachexia