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Adjunctive Support for Mood and Chronic Illness: In some cases, NAD injections are used alongside other therapies in the management of mood disorders (like depression and anxiety) or chronic health conditions such as fibromyalgia and Lyme disease, particularly to address symptoms like fatigue and cognitive difficulties

Insulin normally suppresses gluconeogenesis while promoting lipogenesis, however, under insulin resistant states such as T2D, hepatic lipogenesis remains insulin sensitive and suppression of gluconeogenesis is insulin resistant, leading to a metabolic state called selective hepatic insulin resistance (199)