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Patients considering peptide therapy should be aware that they are essentially participating in an uncontrolled experiment with unknown risks and uncertain benefits

Extra caution is appropriate in patients with active cancer, recent cancer, unexplained masses, unexplained weight loss, pregnancy, breastfeeding, known allergy to peptide products, active infection, immune compromise, significant liver or kidney disease, active inflammatory or autoimmune disease flares, unusual clotting history, uncontrolled cardiovascular disease, use of chemotherapy or immune-modifying biologic therapy, and competitive athletes subject to anti-doping rules

Injecting in the evening can interfere with sleep in some patients, so we do not recommend it

Insufficient testing The risk of counterfeits Sterility failures and manufacturing impurities Potential drug interactions Unknown long-term effects More peptide safety resources Blog by Dan Burke, former FDA federal agent PSM's submission to the FDA Pharmacy Compounding Advisory Committee July 23-24 meeting