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15 This review comprehensively introduces the biological role, molecular mechanisms, and progress of ferroptosis in various human diseases

The net G is 12.2 kJ/mol (2.9 kcal/mol), sufficient to drive not only the preceding dehydrogenase step, but also the aldolase and triose phosphate isomerase reactions

While all genes discussed were derived from genetic screens in GBM, their molecular relevance to cancer may have been determined in a different tumor type