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Subpockets A and B are also mostly hydrophobic and with only a few polar groups available to make polar interactions with the ligand

10.1016/j.pharmthera.2005.01.001 104 KumagaiT.SuzukiH.SasakiT.SakaguchiS.MiyairiS.YamazoeY.et al (2012)

Planta 198:365370 Kumar A, Bachhawat AK (2010) OXP1/YKL215c encodes an ATP-dependent 5-oxoprolinase in Saccharomyces cerevisiae: functional characterization, domain structure and identification of actin-like ATP-binding motifs in eukaryotic 5-oxoprolinases