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Heat-treated (tyndallized) biomass and the supernatant (postbiotics) were used for the in vitro and in vivo tests, and FMC was used as a reference inhibitor ( in vitro test was performed on a fecal slurry sample, monitoring the formation of TMA for 1, 3, and 12 h, and choline (50 M) was used as a substrate

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The CASP (Critical Appraisals Skills Programme) randomized control trial (RCT) checklist (Critical Appraisal Skills Programme, ) was used to critically appraise the studies that were RCTs, and the methodological index for non-randomised studies (MINORS) assessment tool (Slim et al ., ) was used to appraise the open-label studies