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Flow cytometry was performed on Beckman Coulter CytoFLEX and data were analyzed with CytExpert 2.4 software

& Wakil, S

By increasing the ubiquitination of the NLRP3 inflammasome, BA-induced TGR5 activation decreased inflammation [49]

BM-MSCs or BM-MSCs-exosome co-treatment caused anti-apoptotic impacts via a meaningful reduction in Bax/Bcl2 ratio and a rise in the expression of mitochondrial mitophagy genes, including Parkin RBR E3 Ubiquitin Protein Ligase ( Parkin ), phosphatase and tensin homolog (PTEN)-induced putative kinase 1 ( PINK1 ), unc-51 like autophagy activating kinase 1 ( ULK1 ), B-cell lymphoma 2/adenovirus E1B 19 kDa protein-interacting protein 3 ( BNIP3L ), autophagy related gene ( ATG5 ), ATG7 and ATG12