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Concentration of pure compounds in Standard stocks were validated by UV-VIS spectroscopy as described elsewhere

Rats were adapted to the wire mesh box in the same manner as that in the von Frey test

Guo Y-Y, Liang N-N, Zhang X-Y, Ren Y-H, Wu W-Z, Liu Z-B, et al

This section systematically reviews current advances in targeted therapies according to the metabolic segments involved (synthesis, transport, catabolism/oxidation, and specific modes of death), with a focus on combination strategies with immunotherapy (Fig