cystine cysteine glutathione C–S bond cleavage fuels production under disulfide reductase deficiency The role of glutathione and

PMID: 38016475 J Nanobiotechnology Dual metabolic intervention nanoplatform co-delivering BAY-876 and L-cystine for Wilms tumor therapy via disulfidptosis-associated cytoskeletal collapse

However, this approach faces several critical limitations

Vitamin B12deficiency can manifest itself in the following clinical pictures: Hyperchromic macrocytic megaloblastic anemia (pernicious anemia, Biermer's anemia, Addison's anemia these are red blood cell maturation disorders) Funicular spinal disease [spinal cord damage] A vitamin B12deficiency confirmed by laboratory diagnostics can occur with: Years of malnutrition and malnutrition (e.g strictly vegetarian diet)

2011;205(1):51.e1-8