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Release of the mucosal mast cell granule chymase, rat mast cell protease-II, during anaphylaxis is associated with the rapid development of paracellular permeability to macromolecules in rat jejunum

doi: 10.3389/fimmu.2025.1687755 Received 18 August 2025 Revised 26 October 2025 Accepted 17 November 2025 Published 16 December 2025 Volume 16 - 2025 Edited by Karina Pino-Lagos, University of the Andes, Chile Reviewed by Jaxaira Maggi, Spanish National Research Council (CSIC), Spain Noymar Luque-Campos, INSERM U1183 Institut de Mdecine Rgnratrice et de Biothrapie (IRMB), France Updates Copyright 2025 Hu, Zhao, Dai, Wu, Tang, Zhang, Jiang, Rui and Liu

Funding The laboratory of Haematology was supported by the Foundation Against Cancer, the Fonds National de la Recherche Scientifique (FNRS, Belgium) and the Fonds Spciaux de la Recherche (University of Lige)