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Sybody selectionsmall-scale pull-down assay to identify TGP binders To screen TGP binders at a single-colony level, sybodies expressed in the periplasmic space were extracted first as follows

However, definitive superiority could not be established due to insufficient control data from one expedition

Therefore, current evidence and clinical guidelines support the early empirical supplementation of key nutrientsincluding water-soluble vitamins (B 1 , B 6 , folate), zinc, and fat-soluble vitaminseven in the absence of definitive laboratory confirmation [102]