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This promoter is active in neural crest cells, and driving MYCN overexpression in these progenitor cells of NB causes the animals (Th- MYCN ) to develop tumors that closely resemble human NB (43)

Initial assessment: Serum B12 is measured using immunoassay techniques, with results reported in nanograms per litre (ng/L) or picomoles per litre (pmol/L)