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The significant production of ROS alters the phenotype of innate immune cells, rendering the TME toxic [137, 184,185,186]

In this study, we reported an increase in ferric iron in patients with acute primary angle-closure glaucoma (the most typical glaucoma with ph-IOP damage) compared with the average population by analyzing free iron levels in peripheral serum

The impact of MPs on emotional cognition in animals, particularly concerning behavioral modifications, reveals substantial disruption to the nervous system

However, like many polymeric carriers, their intrinsic ability to cross the BBB is limited without functional modification