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[9] Concomitant administration of large calcium supplements, thiazide diuretics, or aluminium-containing phosphate binders can potentiate vitamin D-mediated increases in serum calcium or phosphate, demanding periodic laboratory monitoring and dosage adjustments to avert nephrolithiasis or ectopic calcification

As with any supplement, its best suited for those working with a healthcare practitioner to ensure it aligns with their individual health goals and needs

We rarely recommend isolated glutathione for general detox most marketing positioning is overblown but for patients with documented toxic burden being addressed clinically, it is a core piece

Okamoto et al., 1999