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It suggests that glutathione and other antioxidants, far from interfering with the activity of chemotherapy, appear to reduce side effects without decreasing efficacy and may, in fact, improve the efficacy of the chemotherapy in fighting cancer

Indeed, loss of glutathione peroxidase 4, a oxidation-resistant selenoprotein that utilizes GSH, leads to lipid peroxidation and subsequent ferroptosis, which is also found in epilepsy models ( The NADPH oxidase (NOX) family of enzymes is another relevant major source of ROS in the context of epilepsy as evidenced by activation of NOX2 by kainate-induced SE (Patel et al., 2005)

Urology 59:575578 Ullian ME, Gelasco AK, Fitzgibbon WR, Beck CN, Morinelli TA (2005) N-acetylcysteine decreases angiotensin ii receptor binding in vascular smooth muscle cells

[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Li, Z., He, X., Xing, S., Ni, J., Zhang, W.et al