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Finally, most current studies are based on cell lines (such as ELT3) or animal models, whose tumor microenvironments and drug metabolism differ from those in the human uterus

no claimed effects in humans

Tissue homogenate supernatant mixed with thiobarbituric acid was used to evaluate the malondialdehyde (MDA) content by measuring the absorbance at 532 nm

This raises the notion that perhaps within konzo-prone regions of sub-Saharan Africa there may be genetic variants of GPx3, or genes related to associated pathways that circulate which could alter gene expression and subsequently cause a reduction of protein abundances in these populations