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The AsGSTU15 fused with the green fluorescent protein (35S::AsGSTU15-GFP) was transformed in tobacco leaf, and expressed in both cytoplasm and nucleus of tobacco epidermal cells, suggesting the localization of AsGSTU15 protein in these regions (Fig

Notably, SHMT2 is a mitochondrial enzyme contributory to one-carbon metabolism by converting serine and tetrahydrofolate (THF) into glycine for GSH synthesis and a one-carbon unit, 5,10-methylenetetrahydrofolate (5,10-CH 2 -THF), for dTTP synthesis 35 , respectively

GPX4 may initiate hepatocyte ferroptosis via mitophagy and the destruction of mitochondria caused by ROS-induced damage [19]

doi: 10.1084/jem.20201129 134 Von NussbaumF.LiV