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Description

A shared mechanism underlies both copper-induced cell death and dysregulation of copper homeostasis

SILICON 13:31533162

[PubMed: 14532269] 55

Given the dismal prognosis of PC treatment is hindered by a dense desmoplastic stroma, profound hypoxia, limited T-cell infiltration, and abundant immunosuppressive myeloid populations, together forming physical and immunological barriers to effective therapy