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In this study, we did not examine the effects of isosteatic acid on spleen function since the company did not disclose the detailed information of excipients including isostearic acid

Here we used such iPSC-derived complex liver organoids to assess the specific impact of ALGS-causing mutations on parenchymal and non-parenchymal liver cells, their role on bile duct formation and survival, and the interactions between signaling pathways suspected to play a role in ALGS pathophysiology

Hepatic steatosis The accumulation of stored lipids, most notably triglycerides, to abnormally high levels in the liver

ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures