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Intranasal administration is valued as a non-invasive means of both systemic and local administration with good bioavailability, rapid onset, and targeted effects on the central nervous system [13, 14]

6 Peripheral glial cells (satellite glial cells) may contribute to NPP development Satellite glial cells (SGCs), the main cell type mediating myelin generation in the peripheral nervous system, surround sensory ganglion neurons in a circular arrangement at a distance of approximately 20 nm