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Compared to HYAL1, HYAL2 and PH-20, the biological activity and functional significance of HYAL3, HYAL4, and HYALP1 are relatively lower [27]

In one mouse experiment where cancer cells were implanted, adding BPC-157 did not significantly shrink or grow the tumors they basically remained unchanged

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Conversely, p53 has also been reported to inhibit ferroptosis in cancer cells under cysteine deprivation by regulating the transcriptional target cyclin-dependent kinase inhibitor 1A and limiting erastin-induced ferroptosis by blocking dipeptidyl peptidase-4 activity in a transcription-independent manner (43,44)