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Description

As we age, stomach acid production can decline (atrophic gastritis), which makes it harder to extract B12 from food or pills

These effects are generally mild to moderate, transient, and show improvement as patients adapt to treatment

PubMed 18

To evaluate this combination, we used the Zero Interaction Potency (ZIP) model, which accounts for independent drug effects and is particularly suited for combinations of agents with differing targets, such as DPI and vincristine (38)