gscpr glutathione Glutathione-Dependent Pathways in Cancer Cells Glutathione – SQRL PEPTIDE LABS

These novel therapies, such as targeted therapy or immunotherapy, might not replace the use of cisplatin in the future, but instead, they will probably be used as adjuvants in combination with cisplatin-based chemotherapy to increase the efficacy and reduce cisplatin-induced toxicities and resistance (Chen and Chang 2019

While this could indicate that flux through the PPP is necessary to compensate for oxidative processes downstream of glycolysis, it is also possible that optimal PPP flux is needed during the initial steps of activation

PMID 28628108

Lung ischemia reperfusion injury was induced by applying a microvascular clamp to the left lung hilum of mice for 1 h, followed by release of the clamp for reperfusion, as previously described [21]