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Rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) when response to other treatments has been inadequate

Nonteratogenic Effects Because of the known effects of nonsteroidal anti-inflammatory drugs on the fetal cardiovascular system (closure of ductus arteriosus), use during pregnancy (particularly late pregnancy) should be avoided

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Over time, you may not experience any side effects at all with the shots.