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Chronic conditions: Kidney or liver disease and blood disorders like polycythemia vera may need special monitoring Medication interactions: Some drugs can affect how your body responds to B12 therapy

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Future trials should also measure important outcomes such as the clinical signs and symptoms of vitamin B 12 deficiency, health related-quality of life, socioeconomic effects, and report adverse events adequately, preferably in a primary care setting. Clinical practice guidelines British Columbia Medical Services Commission (MSC)

These compounds are thought to have a synergistic effect and are essential components necessary for many physiological systems within the body