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HeLa cells were treated with a series of concentrations of buthionine sulfoximine (BSO) for 72 h, a specific inhibitor for the enzyme required in the first step of GSH synthesis (Fig

It has been observed that atopy in individuals increases the risk of developing AA

[DOI] [PubMed] [Google Scholar] 15.Effect of high-glucose levels on protein oxidation in cultured lens cells, and in crystalline and albumin solution and its inhibition by vitamin B6 and N-acetylcysteine: its possible relevance to cataract formation in diabetes

Owing to its high concentration in the cell (~10 3 M) 1 , the GSH/GSSG pair acts as the main intracellular redox buffer, plays a key role in the detoxification of reactive oxygen species (ROS), and participates in redox signalling 2