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Drug metabolizing enzyme expression in rat choroid plexus: effects of in vivo xenobiotics treatment

Additionally, GTPs abrogated dysregulation in hepatic Kelch-like ECH-associated protein 1 and nuclear factor erythroid 2-related factor 2 (Nrf2) and its downstream target gene expression [heme oxygenase 1, NAD(P)H:quinone oxidoreductase 1, and GST] and inhibited tumor necrosis factor-, transforming growth factor-, and interleukin (IL)-1 and IL-6 in the liver of treated mice