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Itaconate, a TCA cycle-derived metabolite produced by macrophages, plays a key role in dampening inflammation and reducing oxidative stress

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Fructose, a monosaccharide, is predominantly transported into cells via GLUT5, a high-affinity fructose transporter, encoded by the solute carrier family 2 member 5 (SLC2A5) gene, independent of insulin stimulation (30)

11: Sikiric P, Seiwerth S, Skrtic A, Staresinic M, Strbe S, Vuksic A, Sikiric S, Bekic D, Penovic T, Drazenovic D, Becejac T, Tepes M, Madzar Z, Novosel L, Beketic Oreskovic L, Oreskovic I, Stupnisek M, Boban Blagaic A, Dobric I