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Drug resistance mechanisms beyond DPP9-NRF2 (255) and AIM2-FOXO3a (258) are also underexploredwhether epigenetic modifications (e.g., DNA methylation of ACSL4), post-translational regulation (e.g., GPX4 ubiquitination), or metabolic rewiring (e.g., alternative antioxidant pathways) drives acquired resistance to ferroptosis inducers requires investigation

Grote, goed opgezette klinische studies die daadwerkelijk aantonen dat dit leidt tot duidelijke verbeteringen in haargroei, ontbreken echter nog

In hypovolemic and hypotensive animals treated with CaBPC157, a prompt and long-lasting significant blood pressure increase without death was demonstrated