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8G), the microglial morphology exhibited amoeboid-like structure under MPTP stimulation, suggesting the M1type phenotypic transformation

Patients with certain genetic profiles respond better to tirzepatide or dual-compound therapy, while others achieve better results through careful dose titration within their original medication

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doi: 10.1002/pros.24683 Summary Keywords Chronic prostatitis, immune cells, microenvironment, oxidative stress, sperm, sperm DNA fragmentation Citation Li J, Jiang Z, Luo W, Tang K, Liang D, Luo X, Liu L, Long Z, Huang H, Chen W and Zhang Y (2026) Research progress on the multidimensional mechanisms underlying impaired spermatogenesis induced by pathological microenvironment remodeling in chronic prostatitis