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Besides contributing to PCOS-associated hyperandrogenism, insulin resistance is also linked the development of impaired glucose tolerance and type 2 diabetes mellitus [48], in both obese and non-obese women with PCOS [49]

[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Shannon CE, Ghasemi R, Greenhaff PL, Stephens FB

Indel VUS or LP variants were modeled using SWISS-MODEL [39] ( and 3D structures of the wild-type and mutant proteins were compared using Pairwise Structure Alignment tool of Protein Data Bank (PDB) [40]

Refinement of the androgen response element based on ChIP-Seq in androgen-insensitive and androgen-responsive prostate cancer cell lines