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Description

Such signaling has been shown to be physiologically relevant, for example, -arrestin signaling mediated by the chemokine receptor CXCR3 was necessary for full efficacy chemotaxis of activated T cells

These changes translated into enhanced maturation of osteoblasts and greater production of bone matrix (e.g Type I collagen) in laboratory experiments

It means the relationship between concentration and results isn't linear

If long-term storage of a reconstituted solution is required, researchers typically aliquot the solution into single-use vials, snap-freeze at -80 C, and thaw only once before use