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Standard Clinical Dosage 200500 mcg daily, delivered as a subcutaneous injection in the abdominal region

Future studies should use lower doses to determine the threshold concentration of B12 in the gut necessary to change the activities of the microbiota, particularly in the Lachnospiraceae populations and how these changes impact microbe-host interactions in the gut with a specific focus on IL-12p40 cytokine production along the GI tract

If requirement becomes less, this shows the success of vitamin b12 injection for dogs therapy and decision of administering maintenance dose is dependent on results of laboratory tests