glutathione gpx4

glutathione gpx4 peroxidase 4 (GPX4) | Expert tips Validated by Glutathione peroxidase 4 inhibition induces

Name: glutathione gpx4 peroxidase 4 (GPX4) | Expert tips Validated by Glutathione peroxidase 4 inhibition induces
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Glutathione peroxidase 4 inhibition induces ferroptosis and mTOR pathway suppression in thyroid cancer Scientific Reports Mitochondrial glutathione redox cycle and interaction with other antioxidant MedLink Neurology GPX4 in cell death, autophagy, and disease PMC GPX4 independent ferroptosisa new strategy in disease's therapy Cell Death Discovery

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Eur J Clin Invest 2011;41:98102

doi: 10.1042/BJ20151227

One involves the generation in the cytosol of 5-methylTHF from methylene THF and the transfer of its methyl group to regenerate methylcobalamin, which then acts as a coenzyme in the regeneration of methionine