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meningitidis genome is characterized by an abundance of homopolymeric DNA repeats (simple sequence DNA repeats, SSRs) that undergo stochastic and reversible mutations (insertion/deletion) at a high frequency by slipped-strand mispairing during DNA synthesis associated with DNA replication or recombination (Saunders et al., 2000

The cluster analysis was then carried out to detect modules, ensuring a minimum of five components per module for both -OMICs (metabolomics and metagenomics) [38, 39]

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