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Description

Data are represented as mean SEM copy number per ng total RNA ( n = 3)

The identity of metabolites was confirmed based on the retention time and accurate m / z of authentic synthesized chemical standards from Sigma-Aldrich, as well as MS2 fragmentation patterns available in HMDB ( and mzCloud database ( Natural isotope correction was performed with AccuCor2 R code ( Labelled ion counts refer to the sum of all labelled forms, in which each form is weighted by the fraction of carbon atoms labelled