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An ongoing phase II clinical trial is evaluating the effects of different doses of bimagrumab (up to 30 mg/kg) in combination with semaglutide for the treatment of obesity

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K.MelvinJ.KhuranaD.KothareS.HardisonH.et al

239 Elevated expression of ATG genes, including ATG4B, ATG4D, ATG5, and BECN1, underscores its mechanistic relevance, 240 and ATG4B knockdown sensitizes cells to therapy