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Liver myeloperoxidase activity To determine liver myeloperoxidase (MPO) activity, liver tissue was homogenized in 1 ml of cold hexdecyltrimethylammonium bromide buffer, sonicated on ice for 10 s and centrifuged at 14,000xg for 30 min at 4 C

To generate a stable HSP90 knockdown cell line, the lentiviral vector pLenti-GV112 puromycin (GeneChem, Shanghai, China) was constructed and used for the corresponding cells by lentivirus-mediated transfection