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Lipid peroxidation is one of the major damage encountered by Phospholipds due to ROS

S.BerryM

Prakash K, Goyal M, Soni A, et al

The specificity of the response was determined by treatment with an IGF-1R specific inhibitor, Picropodophyllin (PPP) that showed reduced BCL2 levels in GNE knockdown cells indicative of apoptotic response (Fig