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SCHEME 2 Effect of -Glu-Glu on Glutamate Receptors in Cultured Hippocampal Cells The binding studies led by Tamborini et al have shown that -Glu-Glu has the best binding affinity for all ionotropic glutamate receptors, including AMPA, kainate, and NMDA receptors (AMPAr, KAr, and ANMDAr), compared to other -Glu-AAs ( The first objective of this study was to determine if -Glu-Glu activated glutamatergic receptors

Results cannot be extrapolated to home microneedling with topical copper peptide serums, which involves less precise delivery at shallower depths

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These models provide a platform for studying acute and chronic demyelination and for testing new therapeutic approaches aimed at enhancing remyelination prior to conducting in vivo experiments