Apr 16 2024 Agamah et al., ScienceOpen, doi:10.58647/DRUGARXIV.PR000010.v1 Network-based multi-omics-disease-drug associations reveal drug repurposing candidates for COVID-19 disease phases In silico study identifying potential drugs beneficial for COVID-19 by integrating transcriptomics, proteomics, metabolomics, lipidomics, and drug data
Steinmann K, Kluwe L, Friedrich RE, Mautner VF, Cooper DN, Kehrer-Sawatzki H
Detoxification of the Body Glutathione also plays a key role in detoxifying the liver and other organs
Additional caution or monitoring may be appropriate in research settings involving: Active cancer- or tumor-related research models, where antioxidant-related pathways may influence cellular-response or treatment-response mechanisms Severe asthma or hypersensitivity-prone research models, as rare sensitivity-related observations have been reported in some experimental contexts Sulfur-sensitive research models, due to Glutathione containing a thiol (sulfur-containing) group Complex hepatic-function or detoxification-related investigations, where antioxidant modulation may influence oxidative-stress or liver-related biomarkers Research conditions, research amounts, protocol duration, administration frequency, and concurrent compounds may influence tolerability observations across experimental settings
