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7 April 2020

doi: 10.1073/pnas.1705768114 43 Acua-CastroviejoDEscamesGVenegasCDaz-CasadoMELima-CabelloELpezLCet al

In order to produce a pharmacological effect, a drug needs to cross the bloodbrain barrier (BBB) in sufficient concentration and interact with a target within the brain

Immunohistochemistry of lung tissues also showed lower expression of GPx4 in bronchial epithelial cells in COPD patients than in non COPD patients (Fig