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In certain cancer cells, such as those in lung cancer, heightened metabolic activity, particularly within mitochondria, is the primary driver of ROS generation [23]

B.RichardsonC.et al

Immunofluorescence analysis and quantification with CellProfiler confirmed that HLA (IRGQs cargo) was accumulated at the cell surface of S10D mutants, mimicking the phenotype of IRGQ KO cells (Figs